Trends in Anti-Epileptic Drug Development
نویسندگان
چکیده
منابع مشابه
Recent trends in epilepsy and anti-epileptic drugs.
Despite an abundance of information on clinical and experimental epilepsy and on the drugs effective in its treatment, we 3rc still without a full undentanding of the inherent etiology of the epileptogenic focus and the mechanism of action of anticonvulsant drugs. In recent years allcolion has therefore been mainly directed towards the elucidation of these factors on a neuropharmacological and ...
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Objectives Decisions regarding choice and dose of anti-epileptic drug (AED) are driven by considering the potential benefits of reducing seizure frequency against the potential harms of alternative AEDs. Such decisions should be made using the best available evidence, which often requires a quantitative synthesis of data from multiple randomised controlled trials (RCT). However, the systematic ...
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The growth of pharma industries has slowed in recent years because of various reasons such as patent expiries, generic competition, drying pipelines, and increasingly stringent regulatory guidelines. Many blockbuster drugs will loose their exclusivity in next 5 years. Therefore, the current economic situation plus the huge generic competition shifted the focus of pharmaceutical companies from t...
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NEED AND PURPOSE OF REVIEW A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA MEDLINE search (1966-2013) was performed using terms newer anti-epileptic drugs, Oxcarbazep...
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Epilepsy represents the most common serious neurological disorder, with a prevalence of 0.4 - 1%. Approximately 30% of patients are resistant to currently available drugs. New anti-epileptic drugs are needed to treat refractory epilepsy, improve upon current therapies, improve the prognosis of epilepsy and to prevent the epileptogenic process. Designing compounds with specific physiological tar...
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ژورنال
عنوان ژورنال: Behavioural Neurology
سال: 1990
ISSN: 0953-4180,1875-8584
DOI: 10.1155/1990/468141